Prior to moving to Allegheny County, Alexander lived in Adams County, Pennsylvania. He was a teamster and hauled goods back and forth between Eastern Pennsylvania and the Pittsburgh area. He moved to the Allegheny County area about 1779 and settled in North Fayette Township on land to the west of land owned by Isaac and Gabriel Walker (and which he possibly purchased from the Walker's). He was accompanied by his wife and his first two sons, John and Thomas.
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